Tuesday, February 10, 2009

The concept of symptom clusters

The concept of symptom clusters -- "a stable group of two or more concurrent symptoms that are related to one another and independent of other symptoms” was advanced some years ago as a viable way of systematically improve the treatment of primarily cancer patients.(1,2) Clusters, even if the concept is not used, are also the common way of describing diseases of unknown etiology: aka “syndromes”.

Ideally clustering should help identify patient subgroups and indicate possible underlying causes.

A couple of CPPS clusters are tentatively singled out below. The "micturition" and "ejaculatory-genital" clusters are the common reason that advice is sought from a urologist, as these, especially frequency and dribbling and sexual disturbances, conspicuously affect daily life.

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(1) Dodd M, Janson S, Facione N, Faucett J, Froelicher ES, Humphreys J, Lee K, Miaskowski C, Puntillo K, Rankin S, Taylor D. Advancing the science of symptom management. J Adv Nurs 33(5):668-676, 2001.
(2) Barsevick AM. The elusive concept of the symptom cluster. Oncol Nurs Forum 34(5):971-980, 2007.

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